A GENETICALLY ENGINEERED nasal spray vaccine for COVID-19 and flu called Delta-19 showed positive preclinical data. Delta-19, being developed by Vivaldi Biosciences, is expected to provide superior protection to both viral respiratory diseases.
Studies using the ferret model resulted in 100% immunized animals that generated high amounts of antibodies against the COVID-19 virus, SARS-CoV-2. Furthermore, the immunized ferrets exhibited negligible amounts of SARS-CoV-2 in their noses and mouths, while high levels of the virus were observed in the control ferrets. Based on the initial results, Delta-19 has the potential to help achieve sterilizing immunity by preventing the replication of SARS-CoV-2 in the upper respiratory tract and transmission to other individuals.
